Exploring plant genomes by RNA-induced gene silencing

Waterhouse, P. M. & Helliwell, C. A. (2003) Exploring plant genomes by RNA-induced gene silencing. Nature Reviews Genetics, 4(1), pp. 29-38.

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The nucleotide sequences of several animal, plant and bacterial genomes are now known, but the functions of many of the proteins that they are predicted to encode remain unclear. RNA interference is a gene-silencing technology that is being used successfully to investigate gene function in several organisms - for example, Caenorhabditis elegans. We discuss here that RNA-induced gene silencing approaches are also likely to be effective for investigating plant gene function in a high-throughput, genome-wide manner.

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208 citations in Scopus
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190 citations in Web of Science®

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ID Code: 65835
Item Type: Journal Article
Refereed: Yes
Keywords: plant RNA, Arabidopsis, Caenorhabditis elegans, gene expression, gene function, gene identification, gene insertion, gene sequence, gene silencing, gene technology, genetic analysis, genetic engineering, genetic enhancement, genome, nonhuman, nucleotide repeat, nucleotide sequence, open reading frame, plant genetics, plant virus, priority journal, protein analysis, protein function, review, Rhizobium radiobacter, rice, RNA degradation, transgene, Forecasting, Genetic Vectors, Genome, Plant, Plant Viruses, Plants, RNA, RNA Interference, Transcription, Genetic, Agrobacterium, Agrobacterium tumefaciens, Animalia, Bacteria (microorganisms), Caenorhabditis, Embryophyta, insertion sequences
DOI: 10.1038/nrg982
ISSN: 1471-0056
Subjects: Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > PLANT BIOLOGY (060700)
Divisions: Current > Schools > School of Earth, Environmental & Biological Sciences
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Copyright Owner: Nature Publishing Group
Deposited On: 08 Jan 2014 04:16
Last Modified: 08 Jan 2014 04:16

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