Virus resistance and gene silencing : killing the messenger
Waterhouse, Peter M., Smith, Neil A., & Wang, Ming-Bo (1999) Virus resistance and gene silencing : killing the messenger. Trends in Plant Science, 4(11), pp. 452-457.
On occasion, virus-derived transgenes in plants can be poorly expressed and yet provide excellent virus resistance, and transgene constructs designed to supplement the expression of endogenous genes can have the effect of co-suppressing themselves and the endogenous genes. These two phenomena appear to result from the same post-transcriptional silencing mechanism, which operates by targeted-RNA degradation. Recent research into RNA-mediated virus resistance and co-suppression has provided insights into the interactions between plant viruses and their hosts, and spawned several models to explain the phenomenon.
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|Item Type:||Journal Article|
|Keywords:||disease resistance, gene targeting, transgene, virus infection|
|Subjects:||Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > GENETICS (060400)
Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > PLANT BIOLOGY (060700)
|Divisions:||Current > Schools > School of Earth, Environmental & Biological Sciences
Current > QUT Faculties and Divisions > Science & Engineering Faculty
|Copyright Owner:||Copyright 1999 Elsevier Ltd. * Trends Journals|
|Deposited On:||13 Jan 2014 00:02|
|Last Modified:||13 Jan 2014 00:03|
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