Adhesive characteristics of low dimensional carbon nanomaterial on actin

Li, Tong, Oloyede, Adekunle, & Gu, YuanTong (2014) Adhesive characteristics of low dimensional carbon nanomaterial on actin. Applied Physics Letters, 104(2), 0237021-0237024.

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The biosafety of carbon nanomaterial needs to be critically evaluated with both experimental and theoretical validations before extensive biomedical applications. In this letter, we present an analysis of the binding ability of two dimensional monolayer carbon nanomaterial on actin by molecular simulation to understand their adhesive characteristics on F-actin cytoskeleton. The modelling results indicate that the positively charged carbon nanomaterial has higher binding stability on actin. Compared to crystalline graphene, graphene oxide shows higher binding influence on actin when carrying positive surface charge. This theoretical investigation provides insights into the sensitivity of actin-related cellular activities on carbon nanomaterial.

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3 citations in Scopus
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4 citations in Web of Science®

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119 since deposited on 15 Jan 2014
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ID Code: 66133
Item Type: Journal Article
Refereed: Yes
Keywords: Actin, Graphene oxide, Graphene, Adhesion
DOI: 10.1063/1.4862200
ISSN: 1077-3118
Subjects: Australian and New Zealand Standard Research Classification > PHYSICAL SCIENCES (020000) > OTHER PHYSICAL SCIENCES (029900) > Biological Physics (029901)
Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300) > Biomaterials (090301)
Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > MECHANICAL ENGINEERING (091300) > Numerical Modelling and Mechanical Characterisation (091307)
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Copyright Owner: Copyright 2014 AIP Publishing LLC
Deposited On: 15 Jan 2014 00:46
Last Modified: 11 Apr 2014 01:57

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