RANKL expression in periodontal disease : where does RANKL come from?
Chen, Bin, Wu, Wenlei, Sun, Weibin, Zhang, Qian, Yan, Fuhua, & Xiao, Yin (2014) RANKL expression in periodontal disease : where does RANKL come from? BioMed Research International, 2014(731039).
Periodontitis is an inflammatory disease characterized by periodontal pocket formation and alveolar bone resorption. Periodontal bone resorption is induced by osteoclasts and receptor activator of nuclear factor-κB ligand (RANKL) which is an essential and central regulator of osteoclast development and osteoclast function. Therefore, RANKL plays a critical role in periodontal bone resorption. In this review, we have summarized the sources of RANKL in periodontal disease and explored which factors may regulate RANKL expression in this disease.
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|Item Type:||Journal Article|
|Keywords:||Receptor activator of nuclear factor-κB ligand (RANKL), Periodontal disease, Bone resorption|
|Subjects:||Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000)
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > DENTISTRY (110500)
|Divisions:||Current > Institutes > Institute of Health and Biomedical Innovation
Current > QUT Faculties and Divisions > Science & Engineering Faculty
|Copyright Owner:||Copyright 2014 Bin Chen et al.|
|Copyright Statement:||This is an open access article distributed under theCreativeCommonsAttribution License,which
permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
|Deposited On:||05 Mar 2014 00:18|
|Last Modified:||17 Mar 2014 05:05|
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