The optimal duration and delay of first aid treatment for deep partial thickness burn injuries
Cuttle, Leila, Kempf, M., Liu, P. Y., Kravchuk, O., & Kimble, R. M. (2010) The optimal duration and delay of first aid treatment for deep partial thickness burn injuries. Burns, 36(5), pp. 673-679.
Using our porcine model of deep dermal partial thickness burn injury, various durations (10min, 20min, 30min or 1h) and delays (immediate, 10min, 1h, 3h) of 15 degrees C running water first aid were applied to burns and compared to untreated controls. The subdermal temperatures were monitored during the treatment and wounds observed weekly for 6 weeks, for re-epithelialisation, wound surface area and cosmetic appearance. At 6 weeks after the burn, tissue biopsies were taken of the scar for histological analysis. Results showed that immediate application of cold running water for 20min duration is associated with an improvement in re-epithelialisation over the first 2 weeks post-burn and decreased scar tissue at 6 weeks. First aid application of cold water for as little as 10min duration or up to 1h delay still provides benefit.
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|Item Type:||Journal Article|
|Additional Information:||Cuttle, Leila
Kimble, Roy M
Research Support, Non-U.S. Gov't
Burns. 2010 Aug;36(5):673-9. doi: 10.1016/j.burns.2009.08.002. Epub 2009 Oct 29.
|Keywords:||Animals, Biopsy, Body Temperature, Burns/*pathology/*therapy, Cicatrix/pathology, Cryotherapy/*methods, Epithelium/pathology, *First Aid, Granulation Tissue/pathology, Swine, Time Factors, Water/*administration & dosage, Wound Healing/physiology|
|ISSN:||1879-1409 (online) 0305-4179 (print)|
|Divisions:||Current > Schools > School of Biomedical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
|Copyright Owner:||Copyright 2009 Elsevier Ltd and ISBI. All rights reserved.|
|Deposited On:||26 Feb 2014 23:50|
|Last Modified:||25 Mar 2014 06:04|
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