Comparison of three different dressings for partial thickness burns in children : study protocol for a randomised controlled trial

Gee Kee, Emma, Kimble, Roy M, Cuttle, Leila, & Stockton, Kellie (2013) Comparison of three different dressings for partial thickness burns in children : study protocol for a randomised controlled trial. Trials, 14(403), pp. 1-8.

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In the paediatric population, pain and distress associated with burn injuries during wound care procedures remain a constant challenge. Although silver dressings are the gold standard for burn care in Australasia, very few high-level trials have been conducted that compare silver dressings to determine which will provide the best level of care clinically. Therefore, for paediatric patients in particular, identifying silver dressings that are associated with lower levels of pain and rapid wound re-epithelialisation is imperative. This study will determine whether there is a difference in time to re-epithelialisation and pain and distress experienced during wound care procedures among Acticoat, Acticoat combined with Mepitel and Mepilex Ag dressings for acute, paediatric partial thickness burns.

Children aged 0 to 15 years with an acute partial thickness (superficial partial to deep partial thickness inclusive) burn injury and a burn total body surface area of </= 10% will be eligible for the trial. Patients will be randomised to one of the three dressing groups:
(1) Acticoat or
(2) Acticoat combined with Mepitel or
(3) Mepilex Ag.
A minimum of 28 participants will be recruited for each treatment group. Primary measures of pain, distress and healing will be repeated at each dressing change until complete wound re-epithelialisation occurs or skin grafting is required. Additional data collected will include infection status at each dressing change, physical function, scar outcome and scar management requirements, cost effectiveness of each dressing and staff perspectives of the dressings.

The results of this study will determine the effects of three commonly used silver and silicone burn dressing combinations on the rate of wound re-epithelialisation and pain experienced during dressing procedures in acute, paediatric partial thickness burn injuries.

Australian New Zealand Clinical Trials Registry ACTRN12613000105741.

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ID Code: 67207
Item Type: Journal Article
Refereed: Yes
Additional Information: Gee Kee, Emma Kimble, Roy M Cuttle, Leila Stockton, Kellie eng Research Support, Non-U.S. Gov't England 2013/11/28 06:00 Trials. 2013 Nov 25;14:403. doi: 10.1186/1745-6215-14-403.
Additional URLs:
Keywords: Child, Burn injuries, Partial thickness, Silver dressings, Healing, Pain, Distress, Randomised clinical trial
DOI: 10.1186/1745-6215-14-403
ISSN: 1745-6215
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000)
Divisions: Current > Schools > School of Biomedical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: © 2013 Gee Kee et al.; licensee BioMed Central Ltd.
Copyright Statement: This is an open access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Deposited On: 26 Feb 2014 22:49
Last Modified: 27 Feb 2014 21:19

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