Burn healing is dependent on burn site : a quantitative analysis from a porcine burn model

Wang, Xue-Qing, Liu, Pei-Yun, Kempf, Margit, Cuttle, Leila, Chang, Allen Hong-En, Wong, Michael, Kravchuk, Olena, Mill, Julie, & Kimble, Roy M. (2009) Burn healing is dependent on burn site : a quantitative analysis from a porcine burn model. Burns, 35(2), pp. 264-269.

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Abstract

This retrospective review examines healing in different sites on a porcine burn model; 24 pairs of burns on 18 pigs from other animal trials were selected for analysis. Each pair of burns was located on the either the cranial or the caudal part of the thoracic ribs region, on the same side of the animal. The burns were 40-50 cm(2) in size and of uniform deep-dermal partial thickness. Caudal burns healed significantly better than cranial burns, demonstrated by earlier closure of wounds, less scar formation and better cosmesis. To our knowledge, this is the first detailed study reporting that burn healing is affected by location on a porcine burn model. We recommend that similar symmetrical burns should be used for future comparative assessments of burn healing.

Impact and interest:

13 citations in Scopus
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14 citations in Web of Science®

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ID Code: 67227
Item Type: Journal Article
Refereed: Yes
Additional URLs:
Keywords: Animals, Burns/*physiopathology, Cicatrix/*physiopathology, Female, Models, Animal, Skin/injuries/*physiopathology, Swine, Thoracic Injuries/*physiopathology, Wound Healing/*physiology
DOI: 10.1016/j.burns.2008.05.030
ISSN: 1879-1409
Divisions: Current > Schools > School of Biomedical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2009 Elsevier
Copyright Statement: This is the author’s version of a work that was accepted for publication in Burns. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Burns, [VOL 35, ISSUE 2, (2009)] DOI: 10.1016/j.burns.2008.05.030
Deposited On: 26 Feb 2014 22:55
Last Modified: 25 Mar 2014 04:58

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