The ocular response to extended wear of a high Dk silicone hydrogel contact lens
Fonn, Desmond, MacDonald, Karen E., Richter, Doris, & Pritchard, Nicola (2002) The ocular response to extended wear of a high Dk silicone hydrogel contact lens. Clinical and Experimental Optometry, 85(3), pp. 176-182.
Purpose: A four-month extended wear clinical trial was conducted to compare the ocular
effects of a high Dk Balafilcon A silicone hydrogel lens and a low Dk HEMA 38.6 per
cent H20 soft lens.
Method: Twenty-four subjects who were adapted to daily wear of soft lenses wore a high
Dk lens in one eye and a low Dk HEMA lens in the other eye for four months on an
extended wear basis after one week of daily wear. Thirteen progress evaluations were
conducted using standard clinical procedures.
Results: Eighteen subjects (75 per cent) completed the study. The high Dk lens induced
significantly less bulbar and limbal injection and corneal vascularisation than the low
Dk HEMA lens (p < 0.05). Epithelial microcysts were observed only in the eyes wearing
the low Dk lens. A significant increase in myopia was found in the eyes wearing the low
Dk HEMA lens (mean = 0.50 D, p < 0.01) compared to the insignificant myopic increase
of 0.06 D in the eyes wearing the high Dk lens. Three subjects developed small infiltrates in the high Dk lens wearing eyes and significantly more post-lens debris was observed under the high Dk lens. Six subjects developed papillary conjunctivitis in the eye wearing silicone hydrogel lenses but only two of those were discontinued from the study.
Conclusion: No hypoxia-related effects were observed with extended wear of the high
Dk Balafilcon A silicone hydrogel lens.
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|Item Type:||Journal Article|
|Keywords:||corneal swelling, epithelial microcysts, limbal injection, myopic shift, silicone hydrogel soft lens, vascularisation|
|Subjects:||Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)|
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300) > Vision Science (111303)
|Divisions:||Current > QUT Faculties and Divisions > Faculty of Health|
Current > Institutes > Institute of Health and Biomedical Innovation
|Copyright Owner:||Copyright 2002 Australian Optometrical Association|
|Copyright Statement:||The contents of this journal from 1998 to 2005 can be freely accessed online via the journal’s web page (see link).|
|Deposited On:||03 Apr 2007|
|Last Modified:||11 Aug 2011 00:08|
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