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Epithelial inclusions in association with mucin ball development in high-oxygen permeability hydrogel lenses

Pritchard, Nicola, Jones, Lyndon, Dumbleton, Kathryn, & Fonn, Desmond (2000) Epithelial inclusions in association with mucin ball development in high-oxygen permeability hydrogel lenses. Optometry and Vision Science, 77(2), pp. 68-72.

Abstract

Debris trapped behind contact lenses may be associated with adverse reactions in extended wear. Although streaks and clumps of cellular material have been reported after overnight wear of conventional materials, recent experience with several high-oxygen permeability (Dk), silicone-containing hydrogel lenses indicates that certain participants are prone to the development of a unique back surface debris. This debris forms as spherical, translucent entities and results in depressions within the ocular surface after lens removal. Little information is known about these spherical bodies, particularly with respect to their composition and development. In this report, we provide photographic evidence of this debris (sometimes termed "mucin balls" or "lipid plugs"), discuss its differential diagnosis and describe a case in which material seems to be embedded in the epithelium as a direct consequence of their presence.

Impact and interest:

32 citations in Scopus
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20 citations in Web of Science®

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ID Code: 6892
Item Type: Journal Article
Additional Information: The contents of this journal can be freely accessed online via the journal's web page (see hypertext link) 12 months after publication.
Additional URLs:
Keywords: mucin balls, high Dk silicone, hydrogel, extended wear, differential diagnosis, microcysts, vacuoles, case report
ISSN: 1538-9235
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300) > Vision Science (111303)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Copyright Owner: Copyright 2000 Lippincott, Williams and Wilkins
Deposited On: 12 May 2008
Last Modified: 11 Aug 2011 00:08

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