Whole-genome sequencing reveals untapped genetic potential in Africa’s indigenous cereal crop sorghum

Mace, Emma S., Tai, Shauishuai, Gilding, Edward K., Li, Yanhong, Prentis, Peter J., Bian, Lianle, Campbell, Bradley C., Hu, Wushu, Innes, David J., Han, Xuelian, Cruickshank, Alan, Dai, Changming, Frere, Celine, Zhang, Haikuan, Hunt, Colleen H., Wang, Xianyuan, Shatte, Tracey, Wang, Miao, Sun, Zhe, Li, Jun, Lin, Xiaozhen, Godwin, Ian D., Jordan, David R. , & Wang, Jun (2013) Whole-genome sequencing reveals untapped genetic potential in Africa’s indigenous cereal crop sorghum. Nature Communications, 4, p. 2320.

View at publisher (open access)


Sorghum is a food and feed cereal crop adapted to heat and drought and a staple for 500 million of the world’s poorest people. Its small diploid genome and phenotypic diversity make it an ideal C4 grass model as a complement to C3 rice. Here we present high coverage (16–45 × ) resequenced genomes of 44 sorghum lines representing the primary gene pool and spanning dimensions of geographic origin, end-use and taxonomic group. We also report the first resequenced genome of S. propinquum, identifying 8 M high-quality SNPs, 1.9 M indels and specific gene loss and gain events in S. bicolor. We observe strong racial structure and a complex domestication history involving at least two distinct domestication events. These assembled genomes enable the leveraging of existing cereal functional genomics data against the novel diversity available in sorghum, providing an unmatched resource for the genetic improvement of sorghum and other grass species.

Impact and interest:

73 citations in Scopus
Search Google Scholar™
53 citations in Web of Science®

Citation counts are sourced monthly from Scopus and Web of Science® citation databases.

These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.

Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.

Full-text downloads:

47 since deposited on 07 Apr 2014
6 in the past twelve months

Full-text downloads displays the total number of times this work’s files (e.g., a PDF) have been downloaded from QUT ePrints as well as the number of downloads in the previous 365 days. The count includes downloads for all files if a work has more than one.

ID Code: 69135
Item Type: Journal Article
Refereed: Yes
Keywords: Sorghum, Genomes, Genetic Improvement, Domestication Events
DOI: 10.1038/ncomms3320
ISSN: 2041-1723
Divisions: Current > Schools > School of Earth, Environmental & Biological Sciences
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Copyright Owner: Copyright 2013 Macmillan Publishers Limited.
Copyright Statement: This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/
Deposited On: 07 Apr 2014 22:20
Last Modified: 09 Apr 2014 05:45

Export: EndNote | Dublin Core | BibTeX

Repository Staff Only: item control page