Antibacterial anthranilic acid derivatives from Geijera parviflora

Shou, Q., Banbury, L. K., Maccarone, A. T., Renshaw, D. E., Mon, H., Griesser, S., Griesser, H. J., Blanksby, S. J., Smith, J. E., & Wohlmuth, H. (2014) Antibacterial anthranilic acid derivatives from Geijera parviflora. Fitoterapia, 93, pp. 62-66.

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Five anthranilic acid derivatives, a mixture I of three new compounds 11′-hexadecenoylanthranilic acid (1), 9′-hexadecenoylanthranilic acid (2), and 7′-hexadecenoylanthranilic acid (3), as well as a new compound 9,12,15-octadecatrienoylanthranilic acid (4) together with a new natural product, hexadecanoylanthranilic acid (5), were isolated from Geijera parviflora Lindl. (Rutaceae). Their structures were elucidated by extensive spectroscopic measurements, and the positions of the double bonds in compounds 1-3 of the mixture I were determined by tandem mass spectrometry employing ozone-induced dissociation. The mixture I and compound 5 showed good antibacterial activity against several Gram-positive strains. © 2013 Elsevier B.V.

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ID Code: 69665
Item Type: Journal Article
Refereed: Yes
Keywords: Anthranilic acid derivative, Antibacterial activity, Geijera parviflora, Rutaceae
DOI: 10.1016/j.fitote.2013.12.008
ISSN: 0367326X (ISSN)
Subjects: Australian and New Zealand Standard Research Classification > CHEMICAL SCIENCE (030000)
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Copyright Owner: Elsevier
Deposited On: 01 Apr 2014 07:28
Last Modified: 09 Apr 2014 12:21

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