Validation of the mainland Chinese version of the inflammatory bowel disease questionnaire (IBDQ) for ulcerative colitis and Crohn's disease
Ren, Wei Hong, Lai, Ming, Chen, Yan, Irvine, E. Jan, & Zhou, Yunxian (2007) Validation of the mainland Chinese version of the inflammatory bowel disease questionnaire (IBDQ) for ulcerative colitis and Crohn's disease. Inflammatory Bowel Diseases, 13(7), pp. 903-910.
Background/Aims Inflammatory bowel disease affects the quality of a patient’s life in many ways, but no validated instrument for measuring disease-specific quality of life in these patients is available for use in Mainland China. The aim of our study is to develop and validate the Mainland Chinese translation of the Inflammatory Bowel Disease Questionnaire for ulcerative colitis and Crohn’s disease, by assessing its construct validity, discriminant ability, reliability and sensitivity to change.
Methods We administered a developed Mainland Chinese version of the Inflammatory Bowel Disease Questionnaire. Ninety-two Mainland Chinese patients (52 with ulcerative colitis and 40 with Crohn’s disease) completed the Mainland Chinese version of the Inflammatory Bowel Disease Questionnaire, the Chinese version of SF-36 and the global scale for general well-being. A subgroup of 71 patients also completed the Mainland Chinese version of the Inflammatory Bowel Disease Questionnaire and the global scales for general well-being on a second occasion. Clinical activity was assessed by the Walmsley and Harvey-Bradshaw simple indices.
Results The Mainland Chinese Inflammatory Bowel Disease Questionnaire scores correlated well with the related SF-36 dimensional scores for all four domains (r=0.51-0.82), SF-36 total scores (r=0.58-0.87), the colitis activity index (r=-0.56-0.74), and the Crohn’s disease activity index (r=-0.64-0.78) as well as with the global scales. The Mainland Chinese Inflammatory Bowel Disease Questionnaire was able to discriminate between active and inactive disease. Cronbach’s α was 0.95 in ulcerative colitis and 0.94 in Crohn’s disease. Test-re-test reliability was excellent (intraclass correlation coefficient 0.69-0.93) when it was repeated in patients whose clinical activity index was stable. In contrast, there was a significant difference between the baseline and follow-up measurements in patients whose clinical activity index was changed.
Conclusions The Mainland Chinese Inflammatory Bowel Disease Questionnaire proved to be a valid, discriminative and reliable instrument for assessing health-related quality of life in patients with ulcerative colitis and Crohn’s disease in Mainland China.
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|Item Type:||Journal Article|
|Additional Information:||For more information, please refer to the journal’s website (see link) or contact the author. Author contact details: firstname.lastname@example.org|
|Keywords:||Inflammatory Bowel Disease, Ulcerative Colitis, Crohn’s Disease, Quality of life, Inflammatory Bowel Disease Questionnaire, Reliability, Validity, Responsiveness|
|Subjects:||Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > NURSING (111000)|
|Divisions:||Current > QUT Faculties and Divisions > Faculty of Health|
Current > Institutes > Institute of Health and Biomedical Innovation
|Copyright Owner:||Copyright 2007 John Wiley & Sons|
|Deposited On:||17 Apr 2007|
|Last Modified:||10 Aug 2011 23:34|
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