Preparation of mesoporous bioglass coated zirconia scaffold for bone tissue engineering
Lin, Feng, Yan, Cheng, Zheng, Wei, Fan, Wei, Adam, Clayton, & Oloyede, Adekunle (2012) Preparation of mesoporous bioglass coated zirconia scaffold for bone tissue engineering. Advanced Materials Research, 365, pp. 209-215.
Porous yttria-stabilized zirconia (YSZ) has been regarded as a potential candidate for bone substitute due to its high mechanical strength. However, porous YSZ is biologically inert to bone tissue. It is therefore necessary to introduce bioactive coatings onto the walls of the porous structures to enhance its bioactivity. In this study, porous YSZ scaffolds were prepared using a replication technique and then coated with mesoporous bioglass due to its excellent bioactivity. The microstructures were examined using scanning electron microscopy and the mechanical strength was evaluated via compression test. The biocompatibility and bioactivity were also evaluated using bone marrow stromal cell (BMSC) proliferation test and simulated body fluid test.
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|Item Type:||Journal Article|
|Keywords:||scaffold, porous structure, mesoporous bioglass, zirconia, compressive strength, porous materials, mechanical strength|
|Subjects:||Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > MATERIALS ENGINEERING (091200) > Ceramics (091201)
Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > MATERIALS ENGINEERING (091200) > Materials Engineering not elsewhere classified (091299)
|Divisions:||Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Past > QUT Faculties & Divisions > Faculty of Built Environment and Engineering
Current > QUT Faculties and Divisions > Science & Engineering Faculty
|Copyright Owner:||Copyright 2011 Trans Tech Publications Ltd.|
|Deposited On:||13 Apr 2014 23:35|
|Last Modified:||12 Mar 2015 07:32|
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