Enantioselective epoxidation of linolenic acid catalysed by cytochrome P450BM3 from Bacillus megaterium

Çelik, Ayhan, Sperandio, Davide, Speight, Robert E., & Turner, Nicholas J. (2005) Enantioselective epoxidation of linolenic acid catalysed by cytochrome P450BM3 from Bacillus megaterium. Organic & Biomolecular Chemistry, 3(15), pp. 2688-2690.

View at publisher (open access)


Cytochrome P450BM3, from Bacillus megaterium, catalyses the epoxidation of linolenic acid 1 yielding 15,16-epoxyoctadeca-9,12-dienoic acid 2 with complete regio- and moderate enantio-selectivity (60% ee). The absolute configuration of the product is tentatively assigned as 15(R),16(S)-. The Michaelis–Menten parameters kcat and Km for the reaction were determined to be 3126 ± 226 min−1 and 24 ± 6 μM respectively.

Impact and interest:

17 citations in Scopus
Search Google Scholar™
12 citations in Web of Science®

Citation counts are sourced monthly from Scopus and Web of Science® citation databases.

These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.

Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.

Full-text downloads:

145 since deposited on 05 May 2014
54 in the past twelve months

Full-text downloads displays the total number of times this work’s files (e.g., a PDF) have been downloaded from QUT ePrints as well as the number of downloads in the previous 365 days. The count includes downloads for all files if a work has more than one.

ID Code: 70983
Item Type: Journal Article
Refereed: Yes
DOI: 10.1039/B506155E
ISSN: 1477-0539
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Copyright Owner: Copyright 2005 Royal Society of Chemistry
Deposited On: 05 May 2014 04:03
Last Modified: 05 May 2014 04:04

Export: EndNote | Dublin Core | BibTeX

Repository Staff Only: item control page