Simultaneous magnetic resonance imaging and consolidation measurement of articular cartilage

Wellard, R. Mark, Ravasio, Jean-Phillippe, Guesne, Samuel, Bell, Christopher, Oloyede, Adekunle, Tevelan, Greg, Pope, James M., & Momot, Konstantin I. (2014) Simultaneous magnetic resonance imaging and consolidation measurement of articular cartilage. Sensors, 14(5), pp. 7940-7958.

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Magnetic resonance imaging (MRI) offers the opportunity to study biological tissues and processes in a non-disruptive manner. The technique shows promise for the study of the load-bearing performance (consolidation) of articular cartilage and changes in articular cartilage accompanying osteoarthritis. Consolidation of articular cartilage involves the recording of two transient characteristics: the change over time of strain and the hydrostatic excess pore pressure (HEPP). MRI study of cartilage consolidation under mechanical load is limited by difficulties in measuring the HEPP in the presence of the strong magnetic fields associated with the MRI technique. Here we describe the use of MRI to image and characterize bovine articular cartilage deforming under load in an MRI compatible consolidometer while monitoring pressure with a Fabry-Perot interferometer-based fiber-optic pressure transducer.

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ID Code: 71096
Item Type: Journal Article
Refereed: Yes
Keywords: fiber interferometers, magnetic resonance imaging, compression, collagen structure, consolidometery
DOI: 10.3390/s140507940
ISSN: 1424-8220
Subjects: Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000)
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > MEDICAL PHYSIOLOGY (111600)
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OTHER MEDICAL AND HEALTH SCIENCES (119900)
Divisions: Current > Schools > School of Biomedical Sciences
Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Copyright Owner: Copyright 2014 MDPI AG
Deposited On: 08 May 2014 00:57
Last Modified: 01 May 2015 05:34

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