Survey of ferroxidase expression and siderophore production in clinical isolates of Pseudomonas aeruginosa
Huston, Wilhelmina M., Potter, Adam J., Jennings, Michael P., Rello, Jordi, Hauser, Alan R., & McEwan, Alastair G. (2004) Survey of ferroxidase expression and siderophore production in clinical isolates of Pseudomonas aeruginosa. Journal of Clinical Microbiology, 42(6), pp. 2806-2809.
Ferroxidase (encoded by the mco gene), a component of a ferrous iron uptake pathway in Pseudomonas aeruginosa, was detected in all of the 35 respiratory clinical isolates surveyed; in contrast, considerable variation in siderophore expression was observed. The ubiquitous expression of this periplasmic ferroxidase suggests that it plays a key role in iron uptake in this opportunistic pathogen.
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