A novel identification method for ultra trace detection of biomolecules using functionalised Surface Enhanced Raman Spectroscopy (SERS)

Hughes, Juanita Maree (2014) A novel identification method for ultra trace detection of biomolecules using functionalised Surface Enhanced Raman Spectroscopy (SERS). Masters by Research thesis, Queensland University of Technology.

Abstract

This thesis developed a new method for measuring extremely low amounts of organic and biological molecules, using Surface enhanced Raman Spectroscopy. This method has many potential applications, e.g. medical diagnosis, public health, food provenance, antidoping, forensics and homeland security. The method development used caffeine as the small molecule example, and erythropoietin (EPO) as the large molecule. This method is much more sensitive and specific than currently used methods; rapid, simple and cost effective. The method can be used to detect target molecules in beverages and biological fluids without the usual preparation steps.

Impact and interest:

8 citations in Web of Science®
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314 since deposited on 03 Jul 2014
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ID Code: 72864
Item Type: QUT Thesis (Masters by Research)
Supervisor: Kiriakous, Emad, Ayoko, Godwin, Sillence, Martin, & Lott, Bill
Keywords: Ultra-trace analysis, Surface Enhanced Raman Spectroscopy (SERS), Nanosensor, Label-free, Erythropoietin (EPO), Caffeine, anti-Doping, Food provenance
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Institution: Queensland University of Technology
Deposited On: 03 Jul 2014 05:19
Last Modified: 08 Sep 2015 05:49

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