Dielectric barrier discharge plasma in Ar/O2 promoting apoptosis behavior in A549 cancer cells

Huang, Jun, Li, Hui, Chen, Wei, Lv, Guo-Hua, Wang, Xing-Quan, Zhang, Guo-Ping, Ostrikov, Kostya, Wang, Peng-Ye, & Yang, Si-Ze (2011) Dielectric barrier discharge plasma in Ar/O2 promoting apoptosis behavior in A549 cancer cells. Applied Physics Letters, 99(25), pp. 253701-1.

View at publisher (open access)

Abstract

The Ar/O2plasma needle in the induction of A549 cancer cells apoptosis process is studied by means of real-time observation. The entire process of programmed cell death is observed. The typical morphological changes of A549 apoptosis are detected by 4′, 6-diamidino-2-phenylindole staining, for example, chromatin condensation and nuclear fragmentation. Cell viability is determined and quantified by neutral red uptake assay, and the survival rate of A549 from Ar/O2plasmas is presented. Further spectral analysis indicates the reactive species, including O and OH play crucial roles in the cell inactivation.

Impact and interest:

28 citations in Scopus
29 citations in Web of Science®
Search Google Scholar™

Citation counts are sourced monthly from Scopus and Web of Science® citation databases.

These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.

Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.

ID Code: 73743
Item Type: Journal Article
Refereed: Yes
DOI: 10.1063/1.3666819
ISSN: 0003-6951
Divisions: Current > QUT Faculties and Divisions > Science & Engineering Faculty
Deposited On: 10 Jul 2014 04:10
Last Modified: 21 Jun 2017 22:01

Export: EndNote | Dublin Core | BibTeX

Repository Staff Only: item control page