A control theoretic paradigm for cell signaling networks : a simple complexity for a sensitive robustness

Araujo, Robyn & Liotta , Lance (2006) A control theoretic paradigm for cell signaling networks : a simple complexity for a sensitive robustness. Current Opinion in Chemical Biology, 10(1), pp. 81-87.

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The fields of molecular biology and cell biology are being flooded with complex genomic and proteomic datasets of large dimensions. We now recognize that each molecule in the cell and tissue can no longer be viewed as an isolated entity. Instead, each molecule must be considered as one member of an interacting network. Consequently, there is an urgent need for mathematical models to understand the behavior of cell signaling networks in health and in disease.

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21 citations in Scopus
17 citations in Web of Science®
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ID Code: 73921
Item Type: Journal Article
Refereed: Yes
Keywords: Signal Transduction, Cell Physiological Phenomena
DOI: 10.1016/j.cbpa.2006.01.002
ISSN: 1879-0402
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000)
Divisions: Current > Institutes > Institute of Health and Biomedical Innovation
Current > Schools > School of Mathematical Sciences
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Deposited On: 15 Jul 2014 23:38
Last Modified: 17 Jul 2014 05:32

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