RF plasma sputtering deposition of hydroxyapatite bioceramics : synthesis, performance, and biocompatibility

Xu, Shuyan, Long, Jidong, Sim, Lina, Diong, Cheong Hoong, & Ostrikov, Kostya (2005) RF plasma sputtering deposition of hydroxyapatite bioceramics : synthesis, performance, and biocompatibility. Plasma Processes and Polymers, 2(5), pp. 373-390.

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Hydroxyapatite (HA) coatings have numerous applications in orthopedics and dentistry, owing to their excellent ability to promote stronger implant fixation and faster bone tissue ingrowth and remodeling. Thermal plasma spray and other plasma-assisted techniques have recently been used to synthesize various calcium phosphate-based bioceramics. Despite notable recent achievements in the desired stoichiometry, phase composition, mechanical, structural, and bio-compatible properties, it is rather difficult to combine all of the above features in a single coating. For example, many existing plasma-sprayed HA coatings fall short in meeting the requirements of grain size and crystallinity, and as such are subject to enhanced resorption in body fluid. On the other hand, relatively poor interfacial bonding and stability is an obstacle to the application of the HA coatings in high load bearing Ti6Al4V knee joint implants. Here, we report on an alternative: a plasma-assisted, concurrent, sputtering deposition technique for high performance biocompatible HA coatings on Ti6Al4V implant alloy. The plasma-assisted RF magnetron co-sputtering deposition method allows one to simultaneously achieve most of the desired attributes of the biomimetic material and overcome the aforementioned problems. This article details the film synthesis process specifications, extensive analytical characterization of the material's properties, mechanical testing, simulated body fluid assessments, biocompatibility and cytocompatibility of the HA-coated Ti6Al4V orthopedic alloy. The means of optimization of the plasma and deposition process parameters to achieve the desired attributes and performance of the HA coating, as well as future challenges in clinical applications are also discussed.

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ID Code: 74165
Item Type: Journal Article
Refereed: Yes
Additional URLs:
Keywords: Biomimetic, Hydroxyapatite, Materials synthesis, Plasma deposition
DOI: 10.1002/ppap.200400094
ISSN: 1612-8850
Divisions: Current > QUT Faculties and Divisions > Science & Engineering Faculty
Deposited On: 21 Jul 2014 00:46
Last Modified: 22 Jul 2014 00:52

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