Rapid on-site evaluation of fine needle aspiration specimens by cytology scientists : a review of 3032 specimens

Shield, P.W., Cosier, J, Ellerby, G., Gartrell, M., & Papadimos, D. (2014) Rapid on-site evaluation of fine needle aspiration specimens by cytology scientists : a review of 3032 specimens. Cytopathology, 25(5), pp. 322-329.

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Abstract

Objectives

To determine: (1) the accuracy of cytology scientists at assessing specimen adequacy by rapid on-site evaluation (ROSE) at fine needle aspiration (FNA) cytology collections; and (2) whether thyroid FNA with ROSE has lower inadequacy rates than non-attended FNAs.

Methods

The ROSE of adequacy for 3032 specimens from 17 anatomical sites collected over a 20-month period was compared with the final report assessment of adequacy. ROSE was performed by 19 cytology scientists. The report profile for 1545 thyroid nodules with ROSE was compared with that for 1536 consecutive non-ROSE thyroid FNAs reported by the same cytopathologists during the study period.

Results

ROSE was adequate in 75% (2276/3032), inadequate in 12% (366/3032) and in 13% (390/3032) no opinion was rendered. Of the 2276 cases assessed as adequate by ROSE, 2268 (99.6%) were finally reported as adequate for assessment; eight specimens had adequacy downgraded on the final report. Fifty eight per cent of cases with a ROSE assessment of inadequate were reported as adequate (212/366), whereas 93% (363/390) with no opinion rendered were reported as adequate. The overall final report adequacy rate for the 3032 specimens was 94% (2843/3032). Confirmation of a ROSE of adequacy at reporting was uniformly high amongst the 19 scientists, ranging from 98% to 100%. The inadequacy rate for thyroid FNAs with ROSE (6%) was significantly (P < 0.0001) lower than for non-ROSE thyroid FNAs (17%). A significantly (P = 0.02) higher proportion of adequate ROSE thyroid specimens was reported with abnormalities, compared with non-ROSE thyroid collections.

Conclusions

Cytology scientists are highly accurate at determining specimen adequacy at ROSE for a wide range of body sites. ROSE of thyroid FNAs can significantly reduce inadequate reports.

Impact and interest:

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6 citations in Web of Science®

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ID Code: 74385
Item Type: Journal Article
Refereed: Yes
Keywords: Fine needle aspiration cytology, rapid on-site evaluation, thyroid
DOI: 10.1111/cyt.12157
ISSN: 0956-5507
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000)
Divisions: Current > Schools > School of Biomedical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Copyright Owner: Copyright 2014 John Wiley & Sons Ltd
Deposited On: 24 Jul 2014 22:17
Last Modified: 24 Jan 2015 05:50

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