Delivery of therapeutic molecules using electrosprayed polymeric particles for applications in tissue engineering
Bock, Nathalie (2014) Delivery of therapeutic molecules using electrosprayed polymeric particles for applications in tissue engineering. PhD by Publication, Queensland University of Technology.
This thesis has developed an innovative technology, electrospraying, that allows biodegradable microparticles to deliver pharmaceuticals that aid bone regeneration. The establishment, characterisation and optimisation of the technique are a step forward in developing an affordable and safe alternative to the products used currently in the clinical setting for the treatment of musculoskeletal disorders. The researcher has also investigated electrospraying as a coating technique on biodegradable structures that are used to replace damaged tissues, in order to provide localised and efficient drug delivery in the site of the defect to help tissue reconstruction.
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|Item Type:||QUT Thesis (PhD by Publication)|
|Supervisor:||Dargaville, Tim, Woodruff, Mia, & Hutmacher, Dietmar|
|Keywords:||Electrospraying, Drug Delivery, Microparticles, Growth Factors, Tissue Engineering, Controlled Release, Electrospinning, Microspheres, Encapsulation, Protein|
|Divisions:||Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Current > QUT Faculties and Divisions > Science & Engineering Faculty
|Institution:||Queensland University of Technology|
|Deposited On:||25 Aug 2014 05:12|
|Last Modified:||04 Sep 2015 01:56|
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