Delivery of therapeutic molecules using electrosprayed polymeric particles for applications in tissue engineering

Bock, Nathalie (2014) Delivery of therapeutic molecules using electrosprayed polymeric particles for applications in tissue engineering. PhD by Publication, Queensland University of Technology.

Abstract

This thesis has developed an innovative technology, electrospraying, that allows biodegradable microparticles to deliver pharmaceuticals that aid bone regeneration. The establishment, characterisation and optimisation of the technique are a step forward in developing an affordable and safe alternative to the products used currently in the clinical setting for the treatment of musculoskeletal disorders. The researcher has also investigated electrospraying as a coating technique on biodegradable structures that are used to replace damaged tissues, in order to provide localised and efficient drug delivery in the site of the defect to help tissue reconstruction.

Impact and interest:

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Full-text downloads:

83 since deposited on 25 Aug 2014
44 in the past twelve months

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ID Code: 74514
Item Type: QUT Thesis (PhD by Publication)
Supervisor: Dargaville, Tim, Woodruff, Mia, & Hutmacher, Dietmar
Keywords: Electrospraying, Drug Delivery, Microparticles, Growth Factors, Tissue Engineering, Controlled Release, Electrospinning, Microspheres, Encapsulation, Protein
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Institution: Queensland University of Technology
Deposited On: 25 Aug 2014 05:12
Last Modified: 04 Sep 2015 01:56

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