Telomerase activity : detection and clinical implications in human cancer

Smith, Robert A. & Lam, Alfred King-Yin (2009) Telomerase activity : detection and clinical implications in human cancer. Clinical Laboratory International, 2, pp. 24-27.

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Abstract

Telomerase is an extremely important enzyme required for the immortalisation of tumour cells. Because the gene is activated in the vast majority of tumour tissues and remains unused in most somatic cells, it represents a marker with huge diagnostic, prognostic and treatment implications in cancer. This article summarises the basic structure and functions of telomerase and considers its clinical implications in colorectal and other cancers.

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ID Code: 74635
Item Type: Journal Article
Refereed: No
Keywords: Telomerase , cancer, colorectal cancer, carcinoma
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > ONCOLOGY AND CARCINOGENESIS (111200) > Cancer Genetics (111203)
Divisions: Current > Schools > School of Biomedical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2009 Reed Business Information
Deposited On: 04 Aug 2014 03:25
Last Modified: 05 Aug 2014 01:24

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