Role of a Mixed Type, Moderate Intensity Exercise Programme After Perpheral Blood Stem Cell Transplantation

Hayes, Sandra C., Davies, Peter S.W., Parker, Tony W., Bashford, John, & Green, Anita A. (2004) Role of a Mixed Type, Moderate Intensity Exercise Programme After Perpheral Blood Stem Cell Transplantation. British Journal of Sports Medicine, 38(3), pp. 304-309.

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Objectives: To evaluate the effect of peripheral blood stem cell transplantation on functional capacity, and to determine the role of a mixed type, moderate intensity exercise programme in the recovery of patients after intensive cancer treatment. Methods: Peak aerobic capacity and muscular strength (upper body, lower body, and handgrip strength) measures were assessed before (PI) and after (PII) transplant and after a 12 week intervention period (PIII). After PII, 12 patients aged 16-64 years were allotted in equal numbers to a control group or exercise intervention group. Results: Mean peak aerobic capacity and muscular strength were reduced after the transplant, with significant (p<0.05) decreases for upper body strength. No change was found in aerobic capacity and muscular strength between PII and PIII for the control group. In contrast, participation in the exercise programme led to significant improvements in peak aerobic capacity (p<0.05) and upper and lower body strength (p<0.01). In addition, values recorded after the three month intervention period were significantly higher than before treatment for peak aerobic capacity (litres/min (p<0.05) and ml/kg/min (p<0.01)) and lower body strength (p<0.01). Conclusion: Intensive treatment for cancer can adversely affect aerobic capacity and muscular strength. A mixed type, moderate intensity exercise programme can help patients to regain fitness and strength within three months. No exercise can exacerbate physical losses resulting from treatment.

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ID Code: 7544
Item Type: Journal Article
Refereed: Yes
DOI: 10.1136/bjsm.2002.003632
ISSN: 0306-3674
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > PUBLIC HEALTH AND HEALTH SERVICES (111700)
Divisions: Current > Research Centres > Centre for Health Research
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2004 BMJ Publishing Group
Copyright Statement: Reproduced in accordance with the copyright policy of the publisher.
Deposited On: 14 May 2007 00:00
Last Modified: 29 Feb 2012 13:04

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