In-hospital mortality rates after a cemented femoral component for displaced neck of femur fractures

Ginsel, Bastiaan, Crawford, Ross W., Whitehouse, Sarah L., & Taher, Ahmad (2013) In-hospital mortality rates after a cemented femoral component for displaced neck of femur fractures. In International Society for Technology in Arthroplasty (ISTA 2013), 16-19 October 2013, Florida, USA.

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This prospective cohort study investigated whether the use of preoperative anticoagulants is an independent risk factor for the outcomes of surgical treatment of patients with a neck of femur fracture.


Data was obtained from a prospectively collected database. All patients admitted for a neck of femur fracture between Nov 2010 and Oct 2011 were included. This resulted in three hundred twenty-eight patients with 330 neck of femur fractures. Four groups were defined; patients preoperatively

(i) on aspirin (n = 105);

(ii) on clopidogrel (n = 28);

(iii) on warfarin (n = 30), and;

(iv) without any anticoagulation history (n = 167, the control group).

The non-warfarin group included the aspirin group, clopidogrel group and the control group. Primary outcome was the in-hospital mortality. Secondary outcomes were the postoperative complications, return to theatre and length of stay.


Thirteen in-hospital deaths were identified, 4 deaths in the aspirin group, 1 death in the clopidogrel group, 2 deaths in the warfarin group and 6 deaths in the control group. No significant difference in the mortality rates was found between the different groups. Also in the secondary outcomes, no significant difference was found between the four groups. A trend to a higher wound complication rate for the warfarin group was detected.


The use of clopidrogel or aspirin pre operatively is not an influence on short term patient outcome for patients with a neck of femur fracture. Surgical procedures should not be delayed to reverse their influence.

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ID Code: 75537
Item Type: Conference Item (Presentation)
Refereed: Yes
Keywords: in-hospital mortality, displaced femoral neck fracture, neck of femur fracture, cemented prosthesis, ASA classification
ISSN: 2049-4408
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > CLINICAL SCIENCES (110300) > Orthopaedics (110314)
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Deposited On: 25 Aug 2014 23:15
Last Modified: 25 Aug 2014 23:15

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