DNA binding study of isophorone in rats and mice
Thier, R., Peter, H., Wiegand, H. J., & Bolt, H. M. (1990) DNA binding study of isophorone in rats and mice. Archives of Toxicology, 64(8), pp. 684-685.
Following isophorone exposure, in a 2-year study with F344 rats and B6C3F1 mice performed under the National Toxicology Program (NTP), an elevated incidence of tumors was observed in male rats (kidney tumors) and male mice (liver tumors). Female rats and mice showed no elevation of tumor rates by isophorone (NTP 1986).
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|Item Type:||Journal Article|
|Keywords:||isophorone, animal experiment, animal tissue, dna binding, female, kidney, letter, liver, male, mouse, nonhuman, priority journal, rat, sex difference, Animal, Cyclohexanones, DNA, Mice, Rats, Rats, Inbred F344, Animalia|
|Divisions:||Current > Schools > School of Clinical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
|Copyright Owner:||Copyright 1990 Springer|
|Deposited On:||16 Oct 2014 00:13|
|Last Modified:||16 Oct 2014 00:13|
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