The effect of sleep deprivation on BOLD activity elicited by a divided attention task
Jackson, Melinda L., Hughes, Matthew E., Croft, Rodney J., Howard, Mark E., Crewther, David, Kennedy, Gerard A., Owens, Katherine, Pierce, Rob J., O'Donoghue, Fergal J., & Johnston, Patrick (2011) The effect of sleep deprivation on BOLD activity elicited by a divided attention task. Brain Imaging and Behavior, 5(2), pp. 97-108.
Sleep loss, widespread in today’s society and associated with a number of clinical conditions, has a detrimental effect on a variety of cognitive domains including attention. This study examined the sequelae of sleep deprivation upon BOLD fMRI activation during divided attention. Twelve healthy males completed two randomized sessions; one after 27 h of sleep deprivation and one after a normal night of sleep. During each session, BOLD fMRI was measured while subjects completed a cross-modal divided attention task (visual and auditory). After normal sleep, increased BOLD activation was observed bilaterally in the superior frontal gyrus and the inferior parietal lobe during divided attention performance. Subjects reported feeling significantly more sleepy in the sleep deprivation session, and there was a trend towards poorer divided attention task performance. Sleep deprivation led to a down regulation of activation in the left superior frontal gyrus, possibly reflecting an attenuation of top-down control mechanisms on the attentional system. These findings have implications for understanding the neural correlates of divided attention and the neurofunctional changes that occur in individuals who are sleep deprived.
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|Item Type:||Journal Article|
|Subjects:||Australian and New Zealand Standard Research Classification > PSYCHOLOGY AND COGNITIVE SCIENCES (170000) > PSYCHOLOGY (170100) > Biological Psychology (Neuropsychology Psychopharmacology Physiological Psychology) (170101)
Australian and New Zealand Standard Research Classification > PSYCHOLOGY AND COGNITIVE SCIENCES (170000) > PSYCHOLOGY (170100) > Sensory Processes Perception and Performance (170112)
|Divisions:||Current > QUT Faculties and Divisions > Faculty of Health
Current > Schools > School of Psychology & Counselling
|Deposited On:||12 Nov 2014 22:17|
|Last Modified:||20 Nov 2014 00:04|
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