Estrogen and the endometrium: lessons learned from gene expression profiling in rodents and human
Groothuis, P. G., Dassen, Hhnm, Romano, A., & Punyadeera, C. (2007) Estrogen and the endometrium: lessons learned from gene expression profiling in rodents and human. Human Reproduction Update, 13(4), pp. 405-417.
To date, research into the biological processes and molecular mechanisms associated with endometrial receptivity and embryo implantation has been a focus of attention, whereas the complex events that occur in the human endometrium during the menstrual and proliferative phase under the influence of estrogen have received little attention. The objective of this review is to provide an update of our current understanding of the actions of estrogen on both human and rodent endometrium, with special emphasis on the regulation of uterine growth and cell proliferation, and the value of global gene expression analysis, in increasing understanding of these processes.
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|Item Type:||Journal Article|
|Additional Information:||Articles free to read on journal website after 12 months|
|Keywords:||estradiol, endometrium, uterus, gene profiling, proliferation, serum estradiol concentrations, oocyte donation, receptor-alpha, uterine, receptivity, preimplantation period, regulated genes, menstrual-cycle, high responders, cross-talk, in-vivo|
|Divisions:||Current > QUT Faculties and Divisions > Faculty of Health|
|Copyright Owner:||Copyright 2007 Oxford University Press|
|Deposited On:||21 Oct 2014 23:55|
|Last Modified:||30 Jan 2015 05:21|
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