Human saliva as a tool to investigate intimate partner violence

Punyadeera, Chamindie (2012) Human saliva as a tool to investigate intimate partner violence. Brain, Behavior, and Immunity, 26(4), pp. 541-542.

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Human saliva mirrors body’s health and well-being and many of the biomolecules present in blood or urine can also be found in salivary secretions. However, biomolecular concentrations in saliva are usually one tenth to one thousandth of the levels in blood (Pfaffe et al., 2011). Sensitive detection technology platforms are therefore required to detect biomolecules in saliva. Another road block to the advancement of salivary diagnostics is the lack of information related to healthy state saliva vs. a diseased saliva, baseline levels and reference ranges and diurnal variations. Saliva has numerous advantages over blood or urine as a diagnostic fluid: (a) the non-invasive nature of sample collection and the simple, safe, painless and cost-effective methods to collect it; (b) unskilled personnel can collect saliva samples at multiple time points; and (c) the total protein concentration is approximately a quarter of that is present in plasma, which makes it easier to investigate low abundance proteins (Pfaffe et al., 2011). Currently, saliva assays are routinely used to determine, diseases such as HIV, drugs and substances of abuse to provide information on exposure and give qualitative information on the type of illicit drug used (Kintz et al., 2009), cortisol levels for diagnosing Cushing’s syndrome (Doi et al., 2008), and use for biomonitoring of exposure to chemicals (Caporossi et al., 2010) to measure hormones (Gröschl, 2009)....

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ID Code: 77930
Item Type: Journal Article
Refereed: Yes
Additional Information: Cited By (since 1996):4
Export Date: 14 October 2014
Correspondence Address: Punyadeera, C.; Saliva Research Group, Tissue Engineering and Microfluidics Laboratory, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Old Cooper Road, St. Lucia, 4072 QLD, Australia; email:
Keywords: Saliva, C reactive protein, autoimmune disease, cardiovascular disease, diabetes mellitus, human, intimate partner violence, mouth cancer, note, pancreas cancer, partner violence, priority journal, protein blood level, saliva level, Biological Markers, C-Reactive Protein, Cardiovascular Diseases, Female, Humans, Inflammation, Spouse Abuse
DOI: 10.1016/j.bbi.2012.02.006
ISSN: 0889-1591
Divisions: Current > Schools > School of Biomedical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2012 Elsevier Inc.
Deposited On: 22 Oct 2014 04:16
Last Modified: 23 Oct 2014 04:06

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