Corneal changes following short-term miniscleral contact lens wear

Vincent, Stephen J., Alonso-Caneiro, David, & Collins, Michael J. (2014) Corneal changes following short-term miniscleral contact lens wear. Contact Lens and Anterior Eye, 37(6), pp. 461-468.

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To examine the influence of short-term miniscleral contact lens wear on corneal shape, thickness and anterior surface aberrations.


Scheimpflug imaging was captured before, immediately following and 3 hours after a short period (3 hours) of miniscleral contact lens wear for 10 young (mean 27 ± 5 years), healthy participants. Natural diurnal variations were considered by measuring baseline diurnal changes obtained on a separate control day without contact lens wear.


Small but significant anterior corneal flattening was observed immediately following lens removal (overall mean 0.02 ± 0.03 mm, p < 0.001) which returned to baseline levels three hours after lens removal. During the three hour recovery period significant corneal thinning (-13.4 ± 10.5 μm) and posterior surface flattening (0.03 ± 0.02 mm) were also observed (both p < 0.01). The magnitude of posterior corneal flattening during recovery correlated with the amount of corneal thinning (r = 0.69, p = 0.03). Central corneal clearance (maximum tear reservoir depth) was not associated with corneal swelling following lens removal (r = -0.24, p > 0.05). An increase in lower-order corneal astigmatism Z(2,2) was also observed following lens wear (mean -0.144 ± 0.075 μm, p = 0.02).


Flattening of the anterior corneal surface was observed immediately following lens wear, while ‘rebound’ thinning and flattening of the posterior surface was evident following the recovery period. Modern miniscleral contact lenses that vault the cornea may slightly influence corneal shape and power but do not induce clinically significant corneal oedema during short-term wear.

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ID Code: 78472
Item Type: Journal Article
Refereed: Yes
Keywords: Miniscleral contact lens, Corneal oedema, Corneal topography, Corneal aberrations, Post-lens tear layer
DOI: 10.1016/j.clae.2014.08.002
ISSN: 1367-0484
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Current > Schools > School of Optometry & Vision Science
Copyright Owner: Copyright 2014 Elsevier
Copyright Statement: This is the author’s version of a work that was accepted for publication in Contact Lens and Anterior Eye. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Contact Lens and Anterior Eye, [VOL 37, ISSUE 6, (2014)] DOI: 10.1016/j.clae.2014.08.002
Deposited On: 10 Nov 2014 00:54
Last Modified: 01 Jan 2016 21:32

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