Novel approaches for SER spectroscopic analysis of protein cofactors
Murat, Sezer, Arumugam, Sivanesan, Jiu-Ju, Feng, & Weidinger, Inez M. (2011) Novel approaches for SER spectroscopic analysis of protein cofactors. In Pramatarova, Lilyana (Ed.) On Biomimetics. InTech, Rijeka, Croatia, pp. 419-438.
Biomimetic systems employed for biotechnological applications i.e. as biosensors or bio fuel cells, require initial formation of conducting support/protein complexes with controlled properties. The specific interaction of the protein with the support determines important qualities of the device such as electrical communication, long-term stability and catalytic efficiency. In this respect the system parameters have to be chosen in a way that high protein loading on the support is achieved while protein denaturation upon adsorption is prevented. The conditions on the surface have to be adjusted in such a way that the desired surface reaction of the protein i.e. electron transfer to either the electrode or a second redox partner, is still guaranteed. Hence the choice of support, its functionlisation as well as the right adjustment of solution parameters play a crucial role in the rational design of these support/protein constructs.
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|Item Type:||Book Chapter|
|Divisions:||Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > QUT Faculties and Divisions > Science & Engineering Faculty
|Copyright Owner:||Copyright 2011 InTech|
|Deposited On:||10 Nov 2014 22:50|
|Last Modified:||07 Oct 2015 23:39|
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