Novel approaches for SER spectroscopic analysis of protein cofactors

Murat, Sezer, Arumugam, Sivanesan, Jiu-Ju, Feng, & Weidinger, Inez M. (2011) Novel approaches for SER spectroscopic analysis of protein cofactors. In Pramatarova, Lilyana (Ed.) On Biomimetics. InTech, Rijeka, Croatia, pp. 419-438.

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Biomimetic systems employed for biotechnological applications i.e. as biosensors or bio fuel cells, require initial formation of conducting support/protein complexes with controlled properties. The specific interaction of the protein with the support determines important qualities of the device such as electrical communication, long-term stability and catalytic efficiency. In this respect the system parameters have to be chosen in a way that high protein loading on the support is achieved while protein denaturation upon adsorption is prevented. The conditions on the surface have to be adjusted in such a way that the desired surface reaction of the protein i.e. electron transfer to either the electrode or a second redox partner, is still guaranteed. Hence the choice of support, its functionlisation as well as the right adjustment of solution parameters play a crucial role in the rational design of these support/protein constructs.

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ID Code: 78571
Item Type: Book Chapter
ISBN: 9789533072715
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Copyright Owner: Copyright 2011 InTech
Deposited On: 10 Nov 2014 22:50
Last Modified: 07 Oct 2015 23:39

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