Numerical investigation of deformation and failure mechanisms of osteopontin-hydroxyapatite interfaces and mineralized collagen fibril arrays

Lai, Zheng Bo (2014) Numerical investigation of deformation and failure mechanisms of osteopontin-hydroxyapatite interfaces and mineralized collagen fibril arrays. PhD thesis, Queensland University of Technology.

[img] Zheng Bo Lai Thesis (PDF 11MB)
Administrators only until 2 December 2017

Abstract

This thesis is a comprehensive study of deformation and failure mechanisms in bone at nano- and micro-scale levels. It explores the mechanical behaviour of osteopontin-hydroxyapatite interfaces and mineralized collagen fibril arrays, through atomistic molecular dynamics and finite element simulations. This thesis shows some main factors contributing to the excellent material properties of bone and provides some guidelines for development of new artificial biological materials and medical implants.

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ID Code: 79191
Item Type: QUT Thesis (PhD)
Supervisor: Yan, Cheng & Oloyede, Kunle
Additional Information: Recipient of 2014 Outstanding Doctoral Thesis Award.
Thesis embargoed until 2nd of December, 2015. Please contact author for more information.
Keywords: Bone, Osteopontin, Hydroxyapatite, Mineralised Collagen Fibril, Biomechanics, Nanomechanics, Deformation and failure mechanisms, Mechanical Behaviour, Molecular dynamics method, Finite element method, ODTA
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Institution: Queensland University of Technology
Deposited On: 15 Jan 2015 03:07
Last Modified: 16 Nov 2016 00:18

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