A poroviscohyperelastic model for numerical analysis of mechanical behavior of single chondrocyte

Nguyen, Trung Dung, Oloyede, Adekunle, & Gu, YuanTong (2016) A poroviscohyperelastic model for numerical analysis of mechanical behavior of single chondrocyte. Computer Methods in Biomechanics and Biomedical Engineering, 19(2), pp. 126-136.

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Abstract

The aim of this paper is to utilize a poroviscohyperelastic (PVHE) model which is developed based on the porohyperelastic (PHE) model to explore the mechanical deformation properties of single chondrocytes. Both creep and relaxation responses are investigated by using FEM models of micropipette aspiration and AFM experiments, respectively. The newly developed PVHE model is compared thoroughly with the SnHS and PHE models. It has been found that the PVHE can accurately capture both creep and stress relaxation behaviors of chondrocytes better than other two models. Hence, the PVHE is a promising model to investigate mechanical properties of single chondrocytes.

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2 citations in Scopus
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ID Code: 79307
Item Type: Journal Article
Refereed: Yes
Additional URLs:
Keywords: Porohyperelastic, poroviscohyperelastic, chondrocyte, finite element analysis, biomechanics
DOI: 10.1080/10255842.2014.996875
ISSN: 1476-8259
Subjects: Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > BIOCHEMISTRY AND CELL BIOLOGY (060100) > Biochemistry and Cell Biology not elsewhere classified (060199)
Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300) > Biomechanical Engineering (090302)
Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > MECHANICAL ENGINEERING (091300) > Numerical Modelling and Mechanical Characterisation (091307)
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Funding:
Copyright Owner: Copyright 2014 Taylor & Francis
Copyright Statement: The Version of Record of this manuscript has been published
and is available in Computer Methods in Biomechanics and Biomedical Engineering <date of publication> http://www.tandfonline.com/ <Article
DOI>.’
Deposited On: 08 Dec 2014 23:31
Last Modified: 16 Mar 2016 23:03

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