A poroviscohyperelastic model for numerical analysis of mechanical behavior of single chondrocyte
Nguyen, Trung Dung, Oloyede, Adekunle, & Gu, YuanTong (2016) A poroviscohyperelastic model for numerical analysis of mechanical behavior of single chondrocyte. Computer Methods in Biomechanics and Biomedical Engineering, 19(2), pp. 126-136.
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The aim of this paper is to utilize a poroviscohyperelastic (PVHE) model which is developed based on the porohyperelastic (PHE) model to explore the mechanical deformation properties of single chondrocytes. Both creep and relaxation responses are investigated by using FEM models of micropipette aspiration and AFM experiments, respectively. The newly developed PVHE model is compared thoroughly with the SnHS and PHE models. It has been found that the PVHE can accurately capture both creep and stress relaxation behaviors of chondrocytes better than other two models. Hence, the PVHE is a promising model to investigate mechanical properties of single chondrocytes.
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|Item Type:||Journal Article|
|Keywords:||Porohyperelastic, poroviscohyperelastic, chondrocyte, finite element analysis, biomechanics|
|Subjects:||Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > BIOCHEMISTRY AND CELL BIOLOGY (060100) > Biochemistry and Cell Biology not elsewhere classified (060199)
Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300) > Biomechanical Engineering (090302)
Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > MECHANICAL ENGINEERING (091300) > Numerical Modelling and Mechanical Characterisation (091307)
|Divisions:||Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > QUT Faculties and Divisions > Science & Engineering Faculty
|Copyright Owner:||Copyright 2014 Taylor & Francis|
|Copyright Statement:||The Version of Record of this manuscript has been published
and is available in Computer Methods in Biomechanics and Biomedical Engineering <date of publication> http://www.tandfonline.com/ <Article
|Deposited On:||08 Dec 2014 23:31|
|Last Modified:||16 Mar 2016 23:03|
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