A systematic review of prescribing criteria to evaluate appropriateness of medications in frail older people

Poudel, A, Peel, NM, Mitchell, C, Nissen, LM, & Hubbard, RE (2014) A systematic review of prescribing criteria to evaluate appropriateness of medications in frail older people. Reviews in Clinical Gerontology, 24(4), pp. 304-318.

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Abstract

This study systematically reviews the published literature regarding inappropriate prescribing in frail individuals aged at least 65 years. Twenty-five of 466 identified studies met the inclusion criteria. All papers measured some surrogate indicators of frailty, such as performance-based tests, cognitive function and functional dependency. Beers criteria were used in 20 studies (74%) to evaluate inappropriate medication use and 36% (9/25) studies used more than one criterion. The prevalence of inappropriate medications ranged widely from 11 to 92%. Only a few studies reported the relationship between potentially inappropriate medication use and surrogate measures of frailty. These diverse findings indicate the need for a standardized measure for assessing appropriateness of medication in frail older individuals. Prescribing tools should address both medication and patient-related factors such as life expectancy and functional status to minimize inappropriate prescribing in frail individuals.

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1 citations in Scopus
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ID Code: 79568
Item Type: Journal Article
Refereed: Yes
Keywords: frailty, inappropriate prescribing, older people, prescribing criteria, prevalence
DOI: 10.1017/S0959259814000161
ISSN: 1469-9036
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > PHARMACOLOGY AND PHARMACEUTICAL SCIENCES (111500) > Clinical Pharmacology and Therapeutics (111502)
Divisions: Current > Schools > School of Clinical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Copyright Owner: Copyright 2014 Cambridge University Press
Deposited On: 18 Dec 2014 22:06
Last Modified: 21 Jan 2016 03:14

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