J-Circos : an interactive Circos plotter

An, Jiyuan, Lai, John, Sajjanhar, Atul, Batra, Jyotsna, Wang, Chenwei, & Nelson, Colleen C. (2015) J-Circos : an interactive Circos plotter. Bioinformatics, 31(9), pp. 1463-1465.

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Abstract

Circos plots are graphical outputs that display three dimensional chromosomal interactions and fusion transcripts. However, the Circos plot tool is not an interactive visualization tool, but rather a figure generator. For example, it does not enable data to be added dynamically, nor does it provide information for specific data points interactively. Recently, an R-based Circos tool (RCircos) has been developed to integrate Circos to R, but similarly, Rcircos can only be used to generate plots. Thus, we have developed a Circos plot tool (J-Circos) that is an interactive visualization tool that can plot Circos figures, as well as being able to dynamically add data to the figure, and providing information for specific data points using mouse hover display and zoom in/out functions. J-Circos uses the Java computer language to enable it to be used on most operating systems (Windows, MacOS, Linux). Users can input data into JCircos using flat data formats, as well as from the GUI. J-Circos will enable biologists to better study more complex chromosomal interactions and fusion transcripts that are otherwise difficult to visualize from next-generation sequencing data.

Impact and interest:

4 citations in Scopus
4 citations in Web of Science®
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ID Code: 79920
Item Type: Journal Article
Refereed: Yes
Additional URLs:
Keywords: J-Circos, Circos Plotter, Bioinformatics, Prostate Cancer, Genetics
DOI: 10.1093/bioinformatics/btu842
ISSN: 1367-4811
Subjects: Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > BIOCHEMISTRY AND CELL BIOLOGY (060100) > Bioinformatics (060102)
Divisions: Current > Schools > School of Biomedical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2014 The Authors
Deposited On: 09 Jan 2015 01:28
Last Modified: 07 Dec 2015 05:51

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