Bacterial adherence and biofilm formation on medical implants : a review

Veerachamy, Suganathan, Yarlagadda, Tejasri, Manivasagam, Geetha, & Yarlagadda, Prasad K.D.V. (2014) Bacterial adherence and biofilm formation on medical implants : a review. Proceedings of the Institution of Mechanical Engineers, Part H : Journal of Engineering in Medicine, 228(10), pp. 1083-1099.

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Abstract

Biofilms are a complex group of microbial cells that adhere to the exopolysaccharide matrix present on the surface of medical devices. Biofilm-associated infections in the medical devices pose a serious problem to the public health and adversely affect the function of the device. Medical implants used in oral and orthopedic surgery are fabricated using alloys such as stainless steel and titanium. The biological behavior, such as osseointegration and its antibacterial activity, essentially depends on both the chemical composition and the morphology of the surface of the device. Surface treatment of medical implants by various physical and chemical techniques are attempted in order to improve their surface properties so as to facilitate bio-integration and prevent bacterial adhesion. The potential source of infection of the surrounding tissue and antimicrobial strategies are from bacteria adherent to or in a biofilm on the implant which should prevent both biofilm formation and tissue colonization. This article provides an overview of bacterial biofilm formation and methods adopted for the inhibition of bacterial adhesion on medical implants

Impact and interest:

11 citations in Scopus
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14 citations in Web of Science®

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ID Code: 80274
Item Type: Journal Article
Refereed: Yes
Keywords: Biofilm;, bacteria infections;, medical implants, nano-polymer coatings, nano-texteured surfaces
DOI: 10.1177/0954411914556137
ISSN: 0954-4119
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Copyright Owner: Copyright 2014 Institution of Mechanical Engineers
Deposited On: 20 Jan 2015 03:02
Last Modified: 24 Jan 2015 02:32

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