Mathematical models of calcium and tight junctions in normal and reconstructed epidermis
Adams, Matthew P. (2015) Mathematical models of calcium and tight junctions in normal and reconstructed epidermis. PhD by Publication, Queensland University of Technology.
This project investigated the calcium distributions of the skin, and the growth patterns of skin substitutes grown in the laboratory, using mathematical models. The research found that the calcium distribution in the upper layer of the skin is controlled by three different mechanisms, not one as previously thought. The research also suggests that tight junctions, which are adhesions between neighbouring skin cells, cannot be solely responsible for the differences in the growth patterns of skin substitutes and normal skin.
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|Item Type:||QUT Thesis (PhD by Publication)|
|Supervisor:||Mallet, Dann & Pettet, Graeme|
|Keywords:||calcium gradient, continuum, epidermis, growing domain, mathematical biology, nonuniform growth, porous medium, reconstructed epidermis, skin substitute, tight junctions|
|Divisions:||Current > Institutes > Institute of Health and Biomedical Innovation
Current > Schools > School of Mathematical Sciences
Current > QUT Faculties and Divisions > Science & Engineering Faculty
|Institution:||Queensland University of Technology|
|Deposited On:||13 Mar 2015 05:18|
|Last Modified:||24 Oct 2015 05:06|
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