Neurobiological correlates of encoding strength of Pavlovian fear conditioned memory

McGuire, Jennifer L., Bergstrom, Hadley C., Prager, Eric M., & Johnson, Luke R. (2010) Neurobiological correlates of encoding strength of Pavlovian fear conditioned memory. In Neuroscience Meeting Planner [Abstracts], Society for Neuroscience, 13 - 17 November 2010, San Diego, California.

View at publisher (open access)


Emotionally significant memories, especially those induced in conjunction with physical and mental trauma, are frequently retained for an individual’s lifetime. How these memories are organized and encoded within neural networks is a fundamental question. The lateral amygdala (LA) is a key nucleus for acquisition and maintenance of associative emotional memories. We used Pavlovian fear conditioning to study how ‘weaker’ and ‘stronger’ memories are encoded in neural networks of the LA. In Pavlovian fear conditioning a neutral stimulus, in this case a tone, is temporally paired with an aversive unconditioned stimulus (US), such as a foot shock. The previously neutral stimulus becomes a conditioned stimulus (CS) capable of eliciting defensive responses. We used time spent freezing when the CS is presented in a neutral context as a dependent variable measure of memory ‘strength’.

Impact and interest:

Citation counts are sourced monthly from Scopus and Web of Science® citation databases.

These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.

Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.

ID Code: 81940
Item Type: Conference Item (Poster)
Refereed: Yes
Keywords: fear conditioning, mitogen activated protein kinase, memory strength
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > NEUROSCIENCES (110900)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Current > Schools > School of Psychology & Counselling
Copyright Owner: Society for Neuroscience
Deposited On: 02 Mar 2015 03:20
Last Modified: 03 Mar 2015 04:01

Export: EndNote | Dublin Core | BibTeX

Repository Staff Only: item control page