Evaluation of left ventricular assist device performance and hydraulic force in a complete mock circulation loop

Timms, Daniel L., Hayne, Mark S., Tan, Andy C., & Pearcy, Mark J. (2005) Evaluation of left ventricular assist device performance and hydraulic force in a complete mock circulation loop. Artificial Organs, 29(7), pp. 573-580.

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Centrifugal pump performance characteristics are vital in determining the ability of a prototype left ventricular assist device (LVAD) to meet the physiological circulation requirements of the cardiovascular system. These characteristics influence the static hydraulic forces encountered by the pump impeller, which determine the required load stiffness of suspension type bearings to minimize impeller touchdown. Performance investigations were conducted on an LVAD design while characterizing the impeller static hydraulic forces of various impeller/volute configurations. The pumps were inserted into a complete systemic and pulmonary mock circulation rig configured to provide suitable nonpulsatile or simulated pulsatile left heart failure environments. The single volute and closed shroud impeller configuration exhibited lowest radial (0.01 N) and axial (3 N) force at nonpulsatile design flow conditions, respectively. Normal hemodynamic conditions of 5.1 L/min at 94mmHg were re-established upon inserting the device into the left heart failure environment, where the pump operated along the nonpulsatile characteristic curve for 2200rpm. The operational limits on this curve were dictated by the required pressure differential across the pump during systolic and diastolic periods. The reduction of left atrial pressure (25 to 8mmHg) indicated the alleviation of pulmonary congestion. The ability for the LVAD to support circulation in a left heart failure environment was successfully demonstrated in the mock circulation loop. The impeller hydraulic force characteristics attained will aid the bearing designer to select the best volute and impeller configuration to minimize impeller touchdown in magnetic, hydrodynamic or mechanical type bearing applications.

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ID Code: 8246
Item Type: Journal Article
Refereed: Yes
Additional Information: For more information, please refer to the journal's website (see hypertext link) or contact the author.
Author contact details: m.pearcy@qut.edu.au
Keywords: Impeller hydraulic thrust, Ventricular assist device, Hemodynamic performance
DOI: 10.1111/j.1525-1594.2005.29093.x
ISSN: 0160-564X
Subjects: Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300) > Biomechanical Engineering (090302)
Divisions: Past > QUT Faculties & Divisions > Faculty of Built Environment and Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2005 Blackwell Publishing
Deposited On: 26 Jun 2007 00:00
Last Modified: 29 Feb 2012 13:13

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