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Endothelial cell serine proteases expressed during vascular morphogenesis and angiogenesis

Aimes, Ronald T., Zijlstra, Andries, Hooper, John D., Ogbourne, Steven M., Sit, Mae-le, Fuchs, Simone, Gotley, David C., Quigley, James P., & Antalis, Toni M. (2003) Endothelial cell serine proteases expressed during vascular morphogenesis and angiogenesis. Thrombosis and Haemostasis, 89(3), pp. 561-572.

Abstract

Many serine proteases play important regulatory roles in complex biological systems, but only a few have been linked directly with capillarry morphogenesis and angiogenesis. Here we provide evidence that serine proteases activities, independent of the plasminogen activation cascade, are required for microvascular endothelial cell reorganization and capillary morphogenesis in vitro.

Impact and interest:

62 citations in Scopus
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55 citations in Web of Science®

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Full-text downloads:

667 since deposited on 27 Jun 2007
70 in the past twelve months

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ID Code: 8271
Item Type: Journal Article
Additional URLs:
Keywords: Serine proteases, endothelial cell, tubule morphogenesis, microvascular, angiogenesis
ISSN: 0340-6245
Subjects: Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > BIOCHEMISTRY AND CELL BIOLOGY (060100) > Cell Metabolism (060104)
Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > BIOCHEMISTRY AND CELL BIOLOGY (060100) > Analytical Biochemistry (060101)
Australian and New Zealand Standard Research Classification > PHYSICAL SCIENCES (020000) > OTHER PHYSICAL SCIENCES (029900) > Medical Physics (029903)
Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > BIOCHEMISTRY AND CELL BIOLOGY (060100)
Divisions: Past > QUT Faculties & Divisions > Faculty of Science and Technology
Copyright Owner: Copyright 2003 Schattauer
Copyright Statement: Reproduced in accordance with the copyright policy of the publisher.
Deposited On: 27 Jun 2007
Last Modified: 29 Feb 2012 23:20

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