Membrane anchored serine preteases: A rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer
Netzel-Arnett, Sarah, Hooper, John D., Szabo, Roman, Madison, Edwin L., Quigley, James P., Bugge, Thomas, & Antalis, Toni M. (2003) Membrane anchored serine preteases: A rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer. Cancer and Metastasis Reviews, 22(2-3), pp. 237-258.
Abstract
Dysregulated proteolysis is a hallmark of cancer. Malignant cells require a range of proteolytic activities to enable growth, survival, and expansion. Serine proteases of the S1 or trypsin-like family have well recognized roles in the maintenance of normal homeostasis as well as in the pathology of diseases such as cancer.
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| ID Code: | 8272 |
|---|---|
| Item Type: | Journal Article |
| Additional Information: | For more information, please refer to the journal's website (see hypertext link) or contact the author. Author contact details: jd.hooper@qut.edu.au |
| Keywords: | serine proteaase, cancer, transmembrane, GPI anchor, TTSP, membrane |
| DOI: | 10.1023/A:1023003616848 |
| ISSN: | 0167-7659 |
| Subjects: | Australian and New Zealand Standard Research Classification > CHEMICAL SCIENCE (030000) > MEDICINAL AND BIOMOLECULAR CHEMISTRY (030400) > Medicinal and Biomolecular Chemistry not elsewhere classified (030499) Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > BIOCHEMISTRY AND CELL BIOLOGY (060100) > Receptors and Membrane Biology (060110) |
| Divisions: | Past > QUT Faculties & Divisions > Faculty of Science and Technology |
| Copyright Owner: | Copyright 2003 Springer |
| Deposited On: | 27 Jun 2007 |
| Last Modified: | 29 Feb 2012 23:20 |
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