Fibroin-based materials support co-cultivation of limbal epithelial and stromal cells

Bray, L.J., George, K.A., Hutmacher, D.W., Chirila, T.V., & Harkin, D.G. (2011) Fibroin-based materials support co-cultivation of limbal epithelial and stromal cells. In Tissue Engineering and Regenerative Medicine International Society European Meeting, 7-10 June 2011, Granada, Spain.


The silk protein fibroin (Bombyx mori) provides a potential substrate for use in ocular tissue reconstruction. We have previously demonstrated that transparent membranes produced from fibroin support cultivation of human limbal epithelial (HLE) cells (Tissue Eng A. 14(2008)1203-11). We extend this body of work to studies of human limbal stromal cell (HLS) growth on fibroin in the presence and absence of serum. Also, we investigate the ability to produce a bi-layered composite scaffold of fibroin with an upper HLE layer and lower HLS layer.

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ID Code: 82953
Item Type: Conference Item (Other)
Refereed: Yes
Divisions: Current > Schools > School of Biomedical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2011 [Please consult the author]
Deposited On: 30 Mar 2015 05:59
Last Modified: 04 Apr 2015 03:32

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