Ambient temperature and the rates of adverse reactions of pertussis vaccines

Guo, Biao, Hu, Wenbiao, Liu, Dawei, & Tong, Shilu (2014) Ambient temperature and the rates of adverse reactions of pertussis vaccines. Clinical Infectious Diseases, 59(6), pp. 904-905.

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Abstract

To the Editor—Diphtheria-tetanus-pertussis whole-cell (DTwP) and acellular (DTaP) vaccines are the 2 main pertussis-contained vaccines. DTwP, developed in the 1930s, has contributed to the reduction of pertussis, but has often been associated with vaccine-related adverse reactions (ARs) [1]. This had severely affected the public confidence in immunization programs, followed by decreased vaccine coverage and pertussis outbreaks in many industrialized countries in the 1970s [2]. DTaP, which was developed in the 1980s and replaced DTwP in developed countries in the 1990s, has been associated with fewer ARs due to removal/reduction of endotoxin [1]. China began replacing DTwP with DTaP in its national immunization programs in December 2007, and its passive Adverse Events Following Immunization (AEFI) surveillance system was established in 2005 [3]. The Intergovernmental Panel on Climate Change Fifth Assessment Report indicates that the planet is warming at...

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ID Code: 83568
Item Type: Journal Article
Refereed: Yes
Keywords: Temperature, Rates of adverse reactions, Pertussis vaccines
DOI: 10.1093/cid/ciu455
ISSN: 1537-6591
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2014 Oxford University Press
Deposited On: 15 Apr 2015 00:05
Last Modified: 07 May 2015 03:48

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