Ambient temperature and the rates of adverse reactions of pertussis vaccines
To the Editor—Diphtheria-tetanus-pertussis whole-cell (DTwP) and acellular (DTaP) vaccines are the 2 main pertussis-contained vaccines. DTwP, developed in the 1930s, has contributed to the reduction of pertussis, but has often been associated with vaccine-related adverse reactions (ARs) . This had severely affected the public confidence in immunization programs, followed by decreased vaccine coverage and pertussis outbreaks in many industrialized countries in the 1970s . DTaP, which was developed in the 1980s and replaced DTwP in developed countries in the 1990s, has been associated with fewer ARs due to removal/reduction of endotoxin . China began replacing DTwP with DTaP in its national immunization programs in December 2007, and its passive Adverse Events Following Immunization (AEFI) surveillance system was established in 2005 . The Intergovernmental Panel on Climate Change Fifth Assessment Report indicates that the planet is warming at...
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|Item Type:||Journal Article|
|Keywords:||Temperature, Rates of adverse reactions, Pertussis vaccines|
|Divisions:||Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
|Copyright Owner:||Copyright 2014 Oxford University Press|
|Deposited On:||15 Apr 2015 00:05|
|Last Modified:||07 May 2015 03:48|
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