Defining a 3-dimensional (3D) in vitro model to study immune cell and renal cell interactions

Afrin, Sadia (2015) Defining a 3-dimensional (3D) in vitro model to study immune cell and renal cell interactions. Masters by Research thesis, Queensland University of Technology.


This study aimed to develop a 3-Dimensional (D) hydrogel system for the co-culture of autologous human renal and immune cells. Previous studies have shown that human renal epithelial cells are able to modulate autologous immune cell responses. However, these studies were undertaken in a standard 2D culture system. The 3D model was developed to re-capitulate these observations within a more physiological relevant in vivo like environment.

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97 since deposited on 18 Aug 2015
75 in the past twelve months

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ID Code: 84754
Item Type: QUT Thesis (Masters by Research)
Supervisor: Klein, Travis, Wilkinson, Ray, & Schrobback, Karsten
Keywords: 3D in vitro model, Hydrogels, Immune modulation, Proximal tubule epithelial cells, T lymphocytes
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Institution: Queensland University of Technology
Deposited On: 18 Aug 2015 06:42
Last Modified: 08 Sep 2015 05:27

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