Longitudinal assessment of corneal subbasal nerve morphology as a potential measure of diabetic peripheral neuropathy

Dehghani, Cirous (2015) Longitudinal assessment of corneal subbasal nerve morphology as a potential measure of diabetic peripheral neuropathy. PhD by Publication, Queensland University of Technology.

Abstract

This thesis represents a significant step forward in developing a validated measure for diabetic peripheral neuropathy – a debilitating and prevalent complication of diabetes. The candidate investigated corneal nerve structure in healthy people as well as in type 1 diabetic individuals in a 4-year longitudinal study. The outcomes of stability of the corneal small nerve fibre in healthy people and evidence of significant decline in diabetic individuals with peripheral neuropathy over time provide justification for the ongoing efforts to establish corneal nerve structure as an objective and appropriate adjunct to conventional measures of peripheral neuropathy.

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30 since deposited on 23 Oct 2015
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ID Code: 84833
Item Type: QUT Thesis (PhD by Publication)
Supervisor: Efron, Nathan, Edwards, Katie, & Pritchard, Nicola
Keywords: Corneal confocal microscopy, Diabetic peripheral neuropathy, Subbasal nerve morphology, Natural history, Corneal nerve quantification
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Current > Schools > School of Optometry & Vision Science
Institution: Queensland University of Technology
Deposited On: 23 Oct 2015 05:05
Last Modified: 24 Jan 2017 22:17

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