The characterisation of Ureaplasma species isolated from the Chorioamnion of women who deliver late Preterm

Sweeney, Emma Louise (2015) The characterisation of Ureaplasma species isolated from the Chorioamnion of women who deliver late Preterm. PhD thesis, Queensland University of Technology.

[img] Emma Sweeney Thesis (PDF 4MB)
Administrators only until 31 June 2017

Abstract

This thesis investigated, for the first time, the prevalence of Ureaplasma species infection within the placentae of women who delivered in the late preterm stages of pregnancy. The presence of these microorganisms was associated with either severe inflammation within the placenta or, for some women, there were no pregnancy complications and these women delivered at term. Ureaplasmas are able to vary their surface exposed lipoproteins and we demonstrated that different host immune responses were generated in vivo to different sized surface lipoproteins. This may explain why ureaplasma infections do not always result in adverse pregnancy and neonatal outcomes.

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ID Code: 84839
Item Type: QUT Thesis (PhD)
Supervisor: Knox, Christine & Stephenson, Sally-Anne
Additional Information: An embargo has been granted by the faculty until June 2017.
Keywords: Ureaplasma parvum, Ureaplasma urealyticum, Chorioamnionitis, Chorioamnion infection, Late preterm birth, Multiple banded antigen, Antigen variation, Host immune response, Inflammation
Divisions: Current > Schools > School of Biomedical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Institution: Queensland University of Technology
Deposited On: 20 Oct 2015 03:02
Last Modified: 26 Oct 2015 02:25

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