Hemi-orolingual angioedema and ACE inhibition after alteplase treatment of stroke
Hill, M. D., Lye, T., Moss, H., Barber, P. A., Demchuk, A. M., Newcommon, N. J., Green, Theresa L., Kenney, C., Cole-Haskayne, A., & Buchan, A. M. (2003) Hemi-orolingual angioedema and ACE inhibition after alteplase treatment of stroke. Neurology, 60(9), pp. 1525-1527.
One hundred seventy-six consecutive patients treated with IV tissue plasminogen activator (tPA) for acute ischemic stroke were examined prospectively, and orolingual angioedema was found in nine (5.1%; 95% CI 2.3 to 9.5). The reaction was typically mild, transient, and contralateral to the ischemic hemisphere. Risk of angioedema was associated with angiotensin-converting enzyme inhibitors (relative risk [RR] 13.6; 95% CI 3.0 to 62.7) and signs on initial CT of ischemia in the insular and frontal cortex (RR 9.1; 95% CI 1.4 to 30.0).
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|Item Type:||Journal Article|
|Subjects:||Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > NURSING (111000) > Nursing not elsewhere classified (111099)|
|Divisions:||Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Current > Schools > School of Nursing
|Deposited On:||08 Jul 2015 23:46|
|Last Modified:||08 Jul 2015 23:46|
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