A reproducible method for automated extraction of brain volumes from 3D human head MR images
Wang, D., Galloway, G. J., De Zubicaray, G. I., Rose, S. E., Chalk, J. B., Doddrell, D. M., & Semple, J. (1998) A reproducible method for automated extraction of brain volumes from 3D human head MR images. Journal of Magnetic Resonance Imaging, 8(2), pp. 480-486.
An automated method for extracting brain volumes from three commonly acquired three-dimensional (3D) MR images (proton density, T1 weighted, and T2-weighted) of the human head is described. The procedure is divided into four levels: preprocessing, segmentation, scalp removal, and postprocessing. A user-provided reference point is the sole operator-dependent input required. The method's parameters were first optimized and then fixed and applied to 30 repeat data sets from 15 normal older adult subjects to investigate its reproducibility. Percent differences between total brain volumes (TBVs) for the subjects' repeated data sets ranged from .5% to 2.2%. We conclude that the method is both robust and reproducible and has the potential for wide application.
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|Item Type:||Journal Article|
|Keywords:||Automated extraction, MRI, Total brain volume estimation|
|Divisions:||Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
|Deposited On:||17 Jul 2015 07:09|
|Last Modified:||20 Jul 2015 02:31|
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