The vertebral venous system in healthy and scoliotic adolescent spines - a 3D MRI investigation

Grant, Caroline A., Newell, Nicolas, Izatt, Maree T., Keenan, Bethany E., Bennett, Damon D., Askin, Geoffrey N., Labrom, Robert D., & Pearcy, Mark J. (2015) The vertebral venous system in healthy and scoliotic adolescent spines - a 3D MRI investigation. In Williams, Richard (Ed.) 26th Annual Scientific Meeting of the Spine Society of Australia, 10-12 April 2015, National Convention Centre, Canberra, ACT. (Unpublished)

[img]
Preview
PDF (13kB)

Abstract

Introduction. The venous drainage system within vertebral bodies (VBs) has been well documented previously in cadaveric specimens. Advances in 3D imaging and image processing now allow for in vivo quantification of larger venous vessels, such as the basivertebral vein. Differences between healthy and scoliotic VB veins can therefore be investigated.

Methods. 20 healthy adolescent controls and 21 AIS patients were recruited (with ethics approval) to undergo 3D MRI, using a 3 Tesla, T1-weighted 3D gradient echo sequence, resulting in 512 slices across the thoraco-lumbar spine, with a voxel size of 0.5x0.5x0.5mm. Using Amira Filament Editor, five transverse slices through the VB were examined simultaneously and the resulting observable vascular network traced. Each VB was assessed, and a vascular network recorded when observable. A local coordinate system was created in the centre of each VB and the vascular networks aligned to this. The length of the vascular network on the left and right sides (with a small central region) of the VB was calculated, and the spatial patterning of the networks assessed level-by-level within each subject.

Results. An average of 6 (range 4-10) vascular networks, consistent with descriptions of the basivertebral vein, were identifiable within each subject, most commonly between T10-L1. Differences were seen in the left/right distribution of vessels in the control and AIS subjects. Healthy controls saw a percentage distribution of 29:18:53 across the left:centre:right regions respectively, whereas the AIS subjects had a slightly shifted distribution of 33:25:42. The control group showed consistent spatial patterning of the vascular networks across most levels, but this was not seen in the AIS group.

Conclusion. Observation and quantification of the basivertebral vein in vivo is possible using 3D MRI. The AIS group lacked the spatial pattern repetition seen in the control group and minor differences were seen in the left/right distribution of vessels.

Impact and interest:

Citation counts are sourced monthly from Scopus and Web of Science® citation databases.

These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.

Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.

Full-text downloads:

4 since deposited on 23 Sep 2015
0 in the past twelve months

Full-text downloads displays the total number of times this work’s files (e.g., a PDF) have been downloaded from QUT ePrints as well as the number of downloads in the previous 365 days. The count includes downloads for all files if a work has more than one.

ID Code: 87653
Item Type: Conference Item (Poster)
Refereed: Yes
Additional URLs:
Keywords: vertebral veins, vertebral venous supply, basivertebral vein, MRI, magnetic resonance imaging, normal spine, healthy control, idiopathic scoliosis, adolescent spine
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Copyright Owner: Copyright 2015 The Authors
Deposited On: 23 Sep 2015 00:26
Last Modified: 27 Sep 2015 05:27

Export: EndNote | Dublin Core | BibTeX

Repository Staff Only: item control page