Multimodal imaging of the collagen and elastic fibre networks in the bovine intervertebral disc
Adam, Clayton, Rouch, Philippe, & Skalli, Wafa (2014) Multimodal imaging of the collagen and elastic fibre networks in the bovine intervertebral disc. In Freeman, Brian J. (Ed.) The Adelaide Centre for Spinal Research - Spinal Research Symposium XII, 14-16 August 2014, Hilton Hotel, Adelaide, SA. (Unpublished)
INTRODUCTION. The intervertebral disc is the largest avascular structure in the human body, withstanding transient loads of up to nine times body weight during rigorous physical activity. The key structural elements of the disc are a gel-like nucleus pulposus surrounded by concentric lamellar rings containing criss-crossed collagen fibres. The disc also contains an elastic fiber network which has been suggested to play a structural role, but to date the relationship between the collagen and elastic fiber networks is unclear.
CONCLUSION. The multimodal transmitted and reflected polarized light microscopy technique developed here allows clear differentiation between the collagen and elastic fiber networks of the intervertebral disc. The ability to image unstained specimens avoids concerns with uneven stain penetration or specificity of staining. In bovine tail discs, the elastic fiber network is intimately associated with the collagen network.
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|Item Type:||Conference Item (Presentation)|
|Keywords:||bovine disc, multimodal imaging, intervertebral disc, disc lamellae, polarized light microscopy, elastin fibres, collagen network|
|Subjects:||Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300) > Biomechanical Engineering (090302)
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > CLINICAL SCIENCES (110300) > Orthopaedics (110314)
|Divisions:||Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Current > QUT Faculties and Divisions > Science & Engineering Faculty
|Copyright Owner:||Copyright 2014 The Authors|
|Deposited On:||23 Sep 2015 03:13|
|Last Modified:||27 Sep 2015 01:25|
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